Science Off CameraPodcast

Episode 40: Prof. Brian Pogue

Brian Pogue is Professor of Engineering at Dartmouth College in the United States. Brian’s research involves creating and exploring new ways to improve medical diagnostics and care using optics and light that affect cancer therapy, light guided surgery and new optical imaging methods.

Tune in to this episode of Science Off Camera to hear about his career path into medical physics, the impact of optical methods in medicine and building a team for interdisciplinary, translational research.

So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Prof. Pogue’s research interests include optics in medicine, biomedical imaging to guide cancer therapy; molecular guided surgery; dose imaging in radiation therapy; Cherenkov light imaging; image guided spectroscopy of cancer; photodynamic therapy; modeling of tumor pathophysiology and contrast

See the following link for more information about Prof. Pogue’s work:

Prof. Brian Pogue at Dartmouth Engineering

Optics in medicine resources at Dartmouth

Links

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Science Off CameraPodcast

Episode 39: Dr. Alessandra Scarpellini

Alessandra Scarpellini is the Head of Sales and Marketing for CrestOptics, and has a PhD in Cell Biology and Biochemistry after a Master degree in Biotechnology. Alessandra developed experience in the microscopy field with Nikon Instruments Europe and Essen Bioscience/Sartorius, before joining CrestOptics, where she oversees business and marketing.

Tune into this episode of Science Off Camera to hear about operating a business during lockdown, Rome without tourists, and the advantages of imaging with a spinning disk system!

Profile photo of Alessandra Scarpellini
So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Industry

CrestOptics is a world leader in scientific optical instrumentation for Fluorescence Microscopy. It has been founded in 2009 by a team of people with a long and proven experience in scientific research, industrial design, and manufacturing of electro-optical systems.

The mission of the company is the production of state of art instruments using optical and electrooptical technology for scientific and industrial applications, key target areas are fluorescence microscopy and spectroscopy.

Links

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Science Off CameraPodcast

Episode 38: Dr. Anja Røyne

Anja Røyne is a researcher, lecturer and author working at the University of Oslo where she has been researching the interfaces between minerals on the nanometer scale to find out their impact on geological structures. Anja’s research has impact on multiple areas related to sustainability and climate change and we talked about in ground carbon storage, clean ways to produce cement and building materials.

Tune in to this episode of Science Off Camera to hear about Anjas book ‘The Elements We Live By’ where she explores the origin and importance of atomic elements and the human impacts of exploiting them. You’ll also hear about spectroscopy, nanotechnology, geology and sustainability and how they are related to each other.

So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Anja is a physicist with a background in solar energy, and has researched geological and geochemical processes, and now working on creating materials with biotechnology. In addition, she runs her own science blog and often contributes to popular science radio programmes and newspapers.

See the following link for more information about Anja’s work:

Homepage 

Anja Royne on Twitter

Anja Royne at the University of Oslo

Anjas book, “The Elements We Live By”

Links

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Science Off CameraPodcast

Episode 37: Dr. Mark Pickering

Dr. Mark Pickering @PickeringLab is a Lecturer/Assistant Professor at the School of Medicine for University College Dublin. Mark is a neurobiologist, microscope hacker, maker, and marine enthusiast who runs the JellyLab.

Tune into this episode of Science Off Camera to hear about imaging jellyfish, 3D printing, outreach giving science back to the general public, and the allure of the sea!

Image
So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Taken from the Mark Pickering lab page:

“My research is focused on understanding the factors underpinning the structure and function of the nervous system. We take a broad approach to this question, ranging from understanding the process of development and repair of myelin in the nervous system, and the impact of mechanical forces on development of the structure of peripheral nerves, through to mapping the dynamic structure of complete nervous systems in simple organisms, specifically the ctenophore Pleurobrachia pileus, In addition to my research on the neurobiology of ctenophores, We are also interested in the biology of the adhesive produced by the colloblast cells in ctenophores, both in terms of its basic biology and its potential applications. The application of simple fabrication methods such as 3D printing to development of low cost and flexible lab tools, such as microscopes, is also a key part of the work of my lab.”

See the JellyLab YouTube page here!

Links

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Science Off CameraPodcast

Episode 36: Prof. Hideaki Kano

Hideaki Kano is a Professor in the department of chemistry at Kyushu University in Japan where he is setting up a new spectroscopy lab. Prof. Kano uses coherent Raman spectroscopy to create functional images of living cells and tissue. The label-free technique allows him to visualize dozens of components in a cell simultaneously for example content of lipids, RNA and proteins.

In this episode of Science Off Camera, tune in to hear about using label-free coherent Raman spectroscopy to measure multi-functional images, as well as the 3 random coincidences that made Prof. Kano discover this technique for his research. 

So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Prof. Kano is highly involved with Raman scattering and Raman spectroscopy, as well as coherent anti-Stokes Raman spectroscopy (CARS).

See the following link for more information about Prof. Kano’s work:

Application note about Prof. Kanos research 

Links

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Science Off CameraPodcast

Episode 35: Dr. Ricardo Henriques

Dr. Ricardo Henriques @HenriquesLab is a Group Leader at Instituto Gulbenkian de Ciência (IGC, Portugal), as well as Honorary Professor at University College London (UCL, UK) and Francis Crick Institute.

Ricardo has a range of interests and experience in the field of imaging, tune in to this episode of Science Off Camera to hear about super resolution algorithms like SRRF, science and imaging in Portugal, and the importance of tinkering with equipment!

So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Taken from the Henriques Lab page: We like to think of ourselves as optical biologists. We focus on addressing biomedical questions by exploiting advancements we develop in optical microscopy. To do so, we create open technology that pushes the boundaries of cellular imaging. All our research and methods are transparent, reproducible and widely available to researchers. In biology, we tackle broad virology, host-pathogen interactions, immunology and cell signalling questions. We do so by establishing new classes of fluorescent probes, high-speed cell-friendly super-resolution methods and computational modelling approaches that, although designed to answer questions of interest in the lab, have extensive cross-disciplinary applications.

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Science Off CameraPodcast

Episode 34: Dr. Jörg Debus

Jörg Debus is a group leader at TU Dortmund in Germany. Jörg’s research covers a broad range of materials such as semiconductors, 2D materials, quantum materials, and more recent experiments in the field of nanotribology, the study of friction on the nanometer scale. Common to all his research that he uses the power of light, optics, and spectroscopy to look at materials.

In this episode of Science Off Camera, tune in to hear about using spins in materials for quantum computing, and what role optics plays in understanding their underlying physics.

So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Dr Debus is currently researching the following topics: Tribology at the nanoscale – fundamental mechanisms, In situ and operando sensing with optical spectroscopy, spins and pseudospins of excitons in tailored MoWSe alloys, and Interactions between magnetic ions and carriers confined in doped semiconductor structures.

See the following links for more information about Dr. Jörg Debus’ work:

Group homepage at TU Dortmund 

Short article about Jörg Debus high-resolution spectroscopy research of quantum spins

Webinar with Jörg Debus about Efficient Spectroscopy for Material Science and Quantum Materials

Links

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Science Off CameraPodcast

Episode 33: Prof. Stephanie Zaleski

Stephanie is an Assistant Professor in the Department of Chemistry and Biochemistry at California State University, East Bay. She recently started her lab in the department of Chemistry and Biochemistry and uses an ultra sensitive measurement technique to detect and identify even single molecules called surface enhanced Raman scattering. She uses her research to preserve works of art, improve delivery of drugs and monitor the environment and is excited about teaching new students about science and how to use spectroscopy.

In this episode of Science Off Camera, tune in to hear about Glass At Risk, sensitive analysis of drug delivery processes, and looking at artwork from Japanese Woodblock prints and Egyptian sculptures. Also, check out Prof. Zaleski’s work on Instagram!

Podcast episode cover art
So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Taken from Prof. Zaleski’s Cal State profile: “My research interests lie at the interface of analytical, physical and materials chemistry. My group studies the fundamental optical properties of plasmonic nanoparticle assemblies and applies the chemical sensitivity of vibrational spectroscopies such as surface-enhanced Raman spectroscopy (SERS) to molecular sensing problems relevant to art conservation, point of care sensing and environmental monitoring.”

Links

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Science Off CameraPodcast

Episode 32: Dr. Emmanuel Reynaud

@ReynaudEmmanuel is a Lecturer and Assistant Professor at the School of Biomolecular and Biomedical Science at University College Dublin.

Emmanuel has many interests based on an upbringing with nature in rural France, ranging from the ocean and glass models, imaging with LEGO, 3D bioprinting, and running a multidisciplinary lab! Tune in to this episode to hear all about it, as well as carbon footprints and making sausages!

Podcast episode cover art
So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

Dr. Reynaud’s research focused on the development of new imaging methods and optical micromanipulations in cell biology. His lab currently applies light sheet microscopy and 3D biological imaging technologies to the understanding of the biological world from single cell to tissue engineered epithelial microtissues (e.g. 3D Bioprinting). He has authored over 80 peer-reviewed articles in English and in French, including articles in Science and Nature Methods, edited and illustrated several books and is actively involved in teaching worldwide, one of his reviews has been cited over a 1,000 times! He is a Fellow of the Royal Microscopy Society and runs the Light Sheet Microscopy community and the ‘Rlab’ (http://therlab.maroz.biz/index.html).

Dr Reynaud’s interests include: Evolution of cell compartmentalization, Evolution of epithelial structure and function, Integrative 3D biological imaging, 3D bioprinting uses in Epithelial Tissue Engineering & Tissue Engineering Organ-on-Chip, Lab-on-a-Chip Systems, and Blaschka Marine Invertebrates models.

Links

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Science Off CameraPodcast

Episode 31: Prof. Christy Landes

Christy Landes is a Professor in Chemistry, and Electrical, Chemical and Biomolecular Engineering at Rice University. Christy’s lab investigates the dynamics of chemical and biochemical events down to the single molecule level and develops microscopic models to understand processes on the macroscale such as protein separation and photocatalysis.

In this episode of Science Off Camera, tune in to hear about Prof Landes’ research combining mathematical and signal processing methods with microscopy and super resolution microscopy and how to keep up with the fast progress in science.

Podcast episode cover art
So we’re essentially doing single-photon imaging with the room lights on, you know, so ask a microscopist if can you do single-photon microscopy, with the room lights on where the camera is three meters away from the slide that you want to image, and they’ll say, you’re crazy, you know, you can’t possibly do it.

Research

“The Landes Research Group develops new spectroscopic tools to image chemical dynamics at interfaces at the limit of a single event. Using this super-resolved chemical knowledge, we create new models to understand and predict macroscale processes like protein separation and photocatalysis.”

Links

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