Page Type: Podcast

Science Off CameraPodcast

Episode 30: Dr. John Tandy

Jon Tandy is a Doctor at London Metropolitan University, as well as the course leader for Natural Sciences BSc and a Senior Lecturer in Physical Chemistry at the School of Human Sciences.

Dr. Tandy investigates the processes that happen in the first fractions of a second when objects in the solar system collide by looking at the light these events produce. However, his research takes place in the lab right here on earth, where he and his colleagues simulate such events.

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I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

Jon’s current research primarily focuses on high-speed imaging and emission spectroscopy of light flashes seen during hypervelocity (> 3 km/s) impacts replicating meteoroids impacting planetary surfaces, allowing an examination of the highly energetic and dynamic chemical reactions. He is also working to develop a new cryogenic source to replicate the icy mixtures found on the surfaces of outer Solar System bodies (e.g. Pluto).

Links

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Science Off CameraPodcast

Episode 29: Dr. Gabi Mandl

Gabi Mandl is a Doctor and scientist in the Lanthanide Research group of Prof. John Capobianco at Concordia University. Lanthanides are luminescent, and Gabi uses them to make luminescent nanoparticles to find new cancer treatments.

In this episode of Science Off Camera, hear about Lanthanide elements and their amazing optical properties, and how Gabi uses them in her research to find new medical therapies.

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

The research of the Lanthanide Research Group involves the synthesis, spectroscopy, and applications of lanthanide-doped nanoparticles. The lab specializes in:

  • Different synthesis techniques of lanthanide-doped nanomaterials
  • Characterization by PXRD, DLS and TEM/SEM
  • Spectroscopic analyses of upconverting and radioluminescent nanoparticles
  • Biomedical applications

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Links

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Science Off CameraPodcast

Episode 28: Prof. Christian Eggeling

Christian Eggeling @AgEggeling is a Professor of super-resolution microscopy, Head of the Department of Biophysical Imaging and Director Institute of Applied Optics and Biophysics at University Jena, as well as Professor of Molecular Immunology at the University Of Oxford.

Tune into this episode of Science Off Camera to hear about Nobel Prizes, working across Europe, and seeing into the nanoscale.

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

The main research interests of the Eggeling Lab are focused on the application and development of ultra-sensitive, live-cell fluorescence microscopy techniques.

“These include super-resolution microscopy or nanoscopy, with a spatial resolution down to the molecular level, and superior to conventional optical microscopes. These advanced microscopes are used to unravel nanoscopic changes at the molecular level in living cells, allowing us to follow cellular immune responses or virus-host interactions. We can visualize previously undetectable molecular interactions (such as protein-protein and protein-lipid interactions), which will shed new light on different molecular pathways triggered at the cell surface and intracellularly, for example during antigen presentation by dendritic cells and T cell activation.”

Links

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Science Off CameraPodcast

Episode 27: Dr. Rebecca Pinals

Rebecca Pinals (@RLPlikesscience) is a scientist and PhD candidate with the Landry Lab (@Landry_Lab) at the University of California, Berkeley. In this episode, tune in to hear about how the optical properties of carbon nanotube nanosensors make them a great tool for sensing of biochemicals, and how Rebecca and her group recently applied nanotubes to detect coronavirus SARS-CoV-2.

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

The Landry Lab is a team of highly interdisciplinary scientists working at the intersection of nanomaterials research, near-infrared microscopy, and their application to the study of life.

“Life takes on unique characteristics at the nano-scale. We are accustomed to making observations and predictions for the behavior of living systems on a scale that is intuitive for the time and size scales of our day-to-day lives. For centuries, scientific advancements have been on a size-scale that is familiar to us: distances in meters, times in seconds, masses in kilograms, and volumes in liters. However, the building blocks of life: proteins, nucleic acids, cells, all live at a very different scale. When we zoom into life down to the molecular level, the scales used to describe distances, times, masses, and volumes shrink to a level that is not intuitive to one accustomed to living life at the macro-scale. Our lab focuses on understanding and exploiting nanomaterials to access information about biological systems stored at the nano-scale.”

Links

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Science Off CameraPodcast

Episode 26: Prof. Anita Mahadevan-Jansen

Anita Mahadevan-Jansen is an Orrin H. Ingram Professor in Biomedical Engineering at Vanderbilt University, as well as the Director of the Biophotonics Centre and the current 2020 Vice President of SPIE. Her research focuses on application of light and light based systems to solve problems in medicine and biology. She is also a Fellow of SPIE, The Optical Society, Society for Applied Spectroscopy, and the American Society for Lasers in Medicine and Surgery.

Anita Mahadevan-Jansen 2019 (cropped).jpg
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

Applications of optical techniques for the diagnosis of pathology. Primary research areas involve the use of fluorescence and Raman spectroscopy for cancer and precancer detection.

Links

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Science Off CameraPodcast

Episode 25: Prof. David Punihaole

David Punihaole is an Assistant Professor at the University of Vermont @uvermont. Prof Punihaole develops new approaches to biological imaging, combining microscopy and spectroscopy to understand how proteins fold in cells and the molecular origins of diseases like Alzheimer’s. Prof. Punihaole notes that conventional microscopy techniques lack the ability to reveal the physiochemical nature of how molecules dynamically interact with their local environment. This knowledge is crucial for not only understanding biological functions but also establishing the molecular basis for human diseases.

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

“To gain a molecular understanding of biological processes, my group is developing a technique that we call Raman Chemical Imaging.  This technique combines the chemical specificity of Raman spectroscopy, which probes environmentally-sensitive molecular vibrations, with sophisticated coherent microscopy techniques.  This method enables us to image the structural dynamics and interactions of biomolecules in their native cellular environment.   We are interested in broadly applying Raman Chemical Imaging to investigate how living cells regulate protein folding, how protein aggregates cause neurodegeneration, and how polymer-based nanoparticles deliver nucleic acids for use in gene therapies.”

Links

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Science Off CameraPodcast

Episode 24: Prof. Paul Maddox

Paul Maddox is the Founder and President of Mizar Imaging, and Associate Professor at The University of North Carolina at Chapel Hill.

The lab of Prof. Maddox uses high-resolution microscopy, quantitative image analysis, cell biology, genetics, biochemistry, and developmental biology to study cell division.

Tune into this episode of Science Off Camera to hear about building microscopes, being in academia and industry, as well as teaching lab classes from a basement!

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

“Dramatic events of cell division have fascinated researchers for over a century, major questions remain about the cellular machines that carry out these steps, and how our collective current knowledge applies to different kinds of cells. Our lab is working to understand how many of these steps in cell division take place. We use multiple model animal cells, to be sure what we discover is true for most cells. We make movies of cells dividing and then measure parameters including the size, speed, packing, and shape of cellular features.”

Links

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Science Off CameraPodcast

Episode 23: Prof. Patrick Vora

Patrick Vora is an Associate Professor and the Director of Quantum Science and Engineering Centre at George Mason University. Prof. Vora’s research interests are focused on studying quantum materials in particular 2D materials and van der Waals heterostructures using various methods of optical spectroscopy.

Tune into this episode of Science Off Camera hear about quantum computing, new materials and spectroscopy.

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

The Vora Lab are a group of physicists and engineers that seek to explore the world of low-dimensional materials.

“Quantum phenomena dominate when materials are reduced to nano-scale dimensions and lead to diverse optical, electronic, and magnetic properties distinct from the bulk form. Using a range of optical and electronic experimental techniques, we study 2D materials (graphene, transition metal dichalcogenides, etc.), 1D materials (carbon nanotubes, DNA photonic wires, nanowire memristors), and heterostructures formed by combining these materials.”

Links

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Science Off CameraPodcast

Episode 22: Dr. Peter O’Toole

Peter O’Toole is the Head of Imaging and Cytometry at the University of York.

Dr O’Toole gained his PhD in the Cell Biophysics Laboratory at the University of Essex and has been involved in many aspects of fluorescence imaging and flow cytometry. Since arriving at York, he has firmly established the Imaging and Cytometry Laboratory as one of the top European centres.

Tune into this episode of Science Off Camera to hear about twitching (the birdwatching kind), building an imaging team, and Peter’s own podcast, #TheMicroscopists!

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

Peter’s research is now focussed on both technology and method development. Peter is a PI on multiple funded grants, including current funding from the RCUK Next Generation Optical Microscopy (NGOM) Call in collaboration with the CRUK-LRI, JEOL and Delmic and KTP/EPSRC funding in collaboration with Phase Focus and BBSRC/JEOL CASE Award to develop a novel CLEM system.

Links

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Science Off CameraPodcast

Episode 21: Prof. Chris Cheatum

Chris Cheatum is a Professor of Chemistry at the University of Iowa. Prof. Cheatum (@ccheatum_uiowa) runs an ultrafast laser lab focusing on a spectroscopic technique called 2D IR spectroscopy.

Tune into this episode of Science Off Camera to hear Prof. Cheatum share how he got involved in science and research, the amazing properties of enzymes, his work with spectroscopy, and the joy of sharing his research and what scientists do with students as young as school level.

Podcast episode cover art
I am very excited to be involved in this kind of research, especially now, where it feels like we can help at least a little bit in the current pandemic situation, in applying these nanotechnologies to probe and understand biological systems

Research

The Cheatum Research Group studies chemical structure and dynamics using 2D IR spectroscopy: “We use lasers to excite molecular vibrations to learn about how the molecules move and how those motions affect the molecule’s reactivity. Use the links above to find out more about our current projects, the people in the group, and to find our recent publications.”

Links

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Google: https://podcasts.google.com/?feed=aHR0cHM6Ly9hbmNob3IuZm0vcy8xZWFlZTdkYy9wb2RjYXN0L3Jzcw%3D%3D